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KMID : 0380420180420010016
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Journal of Prventive Veterinary Medicine
2018 Volume.42 No. 1 p.16 ~ p.21
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Virucidal efficacy of a disinfectant solution composed of citric acid, malic acid and phosphoric acid against avian influenza virus
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Chae Won-Seok
Cha Chun-Nam
Yoo Chang-Yeul
Kim Suk
Lee Hu-Jang
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Abstract
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Highly pathogenic avian influenza virus (HPAIV) damages vital organs and tissues, frequently leading to death in birds, and causes serious economic losses in the poultry industry. In addition, HPAIV can infect humans and other mammals, often with fatal outcomes. In this study, the virucidal efficacy of Clean-Zone®, which contains citric acid, malic acid and phosphoric acid, against avian influenza virus (AIV, H9N2) was investigated. Virucidal efficacy was determined by examining the viability of AIV after contact with the disinfectant in the allantoic membrane of chicken embryos. The disinfectant and AIV were reacted under hard water (HW) and organic matter suspension (OM) condition. AIV was inactivated with 200- and 50-fold dilutions of the disinfectant under HW and OM conditions, respectively. As the disinfectant, Clean-Zone®, has a virucidal efficacy against AIV, it can be used to prevent the spread of animal viral diseases.
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KEYWORD
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Citric acid, malic acid, phosphoric acid, avian influenza virus, disinfectant efficacy
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